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A Mountain View, California, entrepreneur who developed a device to help patients with chronic obstructive pulmonary disease, or COPD, captured the $20,000 first prize in the 19th annual at the University of California, Davis, tonight (May 23). The wearable device uses acoustic sensors, real-time data and artificial intelligence to predict and prevent COPD attacks.

Maria Artunduaga, a physician scientist and CEO of , says her device will revolutionize COPD management. “It flags lung function changes to patients, health care providers and caregivers,” she said. “Patients will be able to act earlier at home, preventing unnecessary ER and hospital visits while preserving lung function and saving lives.”

Big Bang!, organized by the at the university’s , has been helping entrepreneurs start or grow business ventures for almost two decades through the competition as well as the workshops and mentoring it offers. It is open to the public.

Thirteen semifinalists from among 105 entries presented their ventures tonight. They were judged based on their integrated strategy, steps toward implementation and market opportunity. Prizes for Big Bang! — including $18,250 awarded in three Little Bang! pitch and poster competitions — totaled $110,850.

, a team of four graduate students and a researcher from �°������ϲ���Ļ��Ϣ Davis, captured the $7,500 People’s Choice Award and five others for a total of $22,000 and innovation lab services valued at $3,000. The business is developing the use of agricultural by-products to produce insects as nutrient-rich ingredients for feed in the poultry and aquaculture industries.

New biomarker offers lifesaving option

After the death of her grandmother from COPD in 2013, Artunduaga left a career in surgery to focus on public health. While pursuing a Master of Translational Medicine at �°������ϲ���Ļ��Ϣ Berkeley/�°������ϲ���Ļ��ϢSF, she had a eureka moment when she realized that changes in lung resonance could determine trapped air in the lungs.

Respira’s technology continuously tracks lung resonance, a new biomarker of disease evolution and the build-up to a COPD exacerbation. A change in baseline resonance signals an impending attack.

Selected the favorite team by an audience vote, BioMilitus also won the Central Valley Innovation Award, $10,000; the Food, Ag + Health Innovation Award, $3,000; two prizes totaling $1,500 in a Little Bang! competition; and in-kind services from the . Team members are Lydia Palma, Ferisca Putri and Matthew Paddock, all students in biological systems engineering; Trevor Fowles, a student of entomology; and researcher Jesus Fernandez-Bayo.

Other winners

An additional $49,100 in Big Bang prizes were awarded tonight:

• of Newark, Delaware: Software that uses 3D modeling and intensive analysis to provide critical building information and valuable insights to first responders. Engineering Sector Award, $10,000.
• ​ of Ypsilanti, Michigan: Simulation models for hands-on breastfeeding education for health care providers. Health Sector Award, $10,000.
• of Davis, California: A digital platform for wineries to engage customers and extend the personalized experience of the tasting room. Food + Agriculture Sector Award, $10,000. (Also $1,000 in Little Bang!)
• of Davis and Sacramento, California: The reuse of electric-vehicle batteries to store renewable energy. Energy Sector Award, $10,000; CleanStart Award, $2,500; and services at valued at $3,600.
• of Davis, California: Antimicrobially treated advertising products for public transportation. �°������ϲ���Ļ��Ϣ Davis Health Innovation Award, $3,000.