新澳门六合彩内幕信息

Scientists solve the case of the red abalone die-off using new tool: forensic genomics

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Abalone shells among the rocks on a beach
Dead red abalone lie on a beach among the rocks at Fort Ross, Calif., in 2011. Researchers at 新澳门六合彩内幕信息 Davis used forensic genomics to learn that the mass die-off was due to an algal bloom.

In August 2011, thousands of dead red abalone washed up on the beaches of Sonoma County in Northern California. At the time, the cause was unknown, but scientists, including a biologist from the University of California, Davis, learned that a harmful algal bloom was to blame: the causative agent Yessotoxin. 

While discovery of the cause itself is noteworthy, the method by which it was determined could have a profound effect on how wildlife mortality events are investigated in the future. Described in a study published today, April 16, in the journal Nature Communications, the researchers call this new approach 鈥渇orensic genomics.鈥 It involves a combination of field surveys, toxin testing and genomic scans.

In the case of red abalone, the finding was the result of fortunate timing. 

鈥淛ust months before the mortality event, we had sequenced the entire genome of several red abalone in the same area,鈥 said co-author Laura Rogers-Bennett, a senior environmental scientist with the California Department of Fish and Wildlife working at the 新澳门六合彩内幕信息 Davis Bodega Marine Laboratory. 鈥淲hat we had, in essence, was a baseline, so we went back to the same site after the mortalities and did a whole genome scan of the survivors.鈥

With both sets of data in hand, they compared the two groups using a computer program and found a set of clues that pointed them in a very specific direction.

鈥淧arts of the genome were significantly different than what you鈥檇 expect by chance,鈥 said Rogers-Bennett, an affiliated faculty member of the Karen C. Drayer Wildlife Health Center at 新澳门六合彩内幕信息 Davis.

When they investigated those outliers, they found that their function was to aid in detoxification. The results supported their hypothesis that a harmful algal bloom producing a Yessotoxin was the major cause of the mass mortality rather than exposure to other potential toxins.

鈥淥ur technique has widespread applicability and could be useful in finding the causes of other wildlife mortality events,鈥 said Rogers-Bennett. 鈥淲e never would have been able to do this if we hadn鈥檛 done this whole scan of the entire genome in advance.鈥  

The findings demonstrate the value of gathering baseline genetics information about wild populations before a mortality event occurs, even if the baseline samples remain in a freezer until an event emerges.

The study鈥檚 lead author is Pierre de Witt, who was at Stanford University at the time of the research and currently at the University of Gothenburg in Sweden.  

Major funding for the study was provided by the California Department of Fish and Wildlife, with additional funding provided by the National Oceanic and Atmospheric Administration and the Central and Northern California Ocean Observing System.

Media Resources

Kat Kerlin, Research news (emphasis on environmental sciences), 530-750-9195, kekerlin@ucdavis.edu

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Environment Human & Animal Health

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